4YJ5

Crystal structure of PKM2 mutant

Summary for 4YJ5

• Entry DOI: 10.2210/pdb4yj5/pdb
• Descriptor: Pyruvate kinase PKM, PYRUVIC ACID, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: pkm2 mutant, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 228619.47

Authors

Liu, J.-S.,Wu, C.-W.,Wang, W.-C. (deposition date: 2015-03-03, release date: 2016-03-09, Last modification date: 2023-11-15)

• Primary citation: Chen, T.J.,Wang, H.J.,Liu, J.S.,Cheng, H.H.,Hsu, S.C.,Wu, M.C.,Lu, C.H.,Wu, Y.F.,Wu, J.W.,Liu, Y.Y.,Kung, H.J.,Wang, W.C.; Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation; Commun Biol, 2:-, 2019; DOI: 10.1038/s42003-019-0343-4

Experimental method

X-RAY DIFFRACTION (2.41 Å)