4YJ0

Crystal structure of the DM domain of human DMRT1 bound to 25mer target DNA

Summary for 4YJ0

Entry DOI	10.2210/pdb4yj0/pdb
Descriptor	Doublesex- and mab-3-related transcription factor 1, DNA (25-MER), ZINC ION, ... (4 entities in total)
Functional Keywords	transcription factor, protein-dna complex, double zn-finger, transcription
Biological source	Homo sapiens (Human) More
Total number of polymer chains	5
Total formula weight	40208.27
Authors	Murphy, M.W.,Lee, J.K.,Rojo, S.,Gearhart, M.D.,Kurahashi, K.,Banerjee, S.,Loeuille, G.,Bashamboo, A.,McElreavey, K.,Zarkower, D.,Aihara, H.,Bardwell, V.J. (deposition date: 2015-03-02, release date: 2015-05-27, Last modification date: 2022-03-30)
Primary citation	Murphy, M.W.,Lee, J.K.,Rojo, S.,Gearhart, M.D.,Kurahashi, K.,Banerjee, S.,Loeuille, G.A.,Bashamboo, A.,McElreavey, K.,Zarkower, D.,Aihara, H.,Bardwell, V.J. An ancient protein-DNA interaction underlying metazoan sex determination. Nat.Struct.Mol.Biol., 22:442-451, 2015 Cited by PubMed: 26005864 DOI: 10.1038/nsmb.3032 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.814 Å)

Structure validation