4YHH
Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with tigecycline
Summary for 4YHH
Entry DOI | 10.2210/pdb4yhh/pdb |
Related | 2ZM6 |
Descriptor | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (24 entities in total) |
Functional Keywords | protein synthesis, ribosome, antibiotic |
Biological source | Thermus thermophilus HB8 More |
Total number of polymer chains | 21 |
Total formula weight | 765474.86 |
Authors | Schedlbauer, A.,Kaminishi, T.,Ochoa-Lizarralde, B.,Dhimole, N.,Zhou, S.,Lopez-Alonso, J.P.,Connell, S.R.,Fucini, P. (deposition date: 2015-02-27, release date: 2015-04-08, Last modification date: 2024-01-10) |
Primary citation | Schedlbauer, A.,Kaminishi, T.,Ochoa-Lizarralde, B.,Dhimole, N.,Zhou, S.,Lopez-Alonso, J.P.,Connell, S.R.,Fucini, P. Structural characterization of an alternative mode of tigecycline binding to the bacterial ribosome. Antimicrob.Agents Chemother., 59:2849-2854, 2015 Cited by PubMed: 25753625DOI: 10.1128/AAC.04895-14 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.417 Å) |
Structure validation
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