4YC2

Crystal structure of the stabilized inner domain of clade A/E HIV-1 gp120 from E. coli in complex with the antibody A32.

Summary for 4YC2

• Entry DOI: 10.2210/pdb4yc2/pdb
• Related: 3TNM 4H8W 4RQH 4YBL
• Descriptor: The stabilized inner domain of clade A/E HIV-1 gp120 from E. coli, The antibody A32 Fab heavy chain., The antibody A32 Fab light chain., ... (4 entities in total)
• Functional Keywords: adcc, non-neutralizing, anti-hiv-1 env antibody a32, cd4i antibody, clade a/e 93th057, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 6
• Total formula weight: 127131.65

Authors

Tolbert, W.D.,Gohain, N.,Pazgier, M. (deposition date: 2015-02-19, release date: 2016-03-02, Last modification date: 2023-09-27)

• Primary citation: Tolbert, W.D.,Gohain, N.,Veillette, M.,Chapleau, J.P.,Orlandi, C.,Visciano, M.L.,Ebadi, M.,DeVico, A.L.,Fouts, T.R.,Finzi, A.,Lewis, G.K.,Pazgier, M.; Paring Down HIV Env: Design and Crystal Structure of a Stabilized Inner Domain of HIV-1 gp120 Displaying a Major ADCC Target of the A32 Region.; Structure, 24:697-709, 2016; PubMed: 27041594; DOI: 10.1016/j.str.2016.03.005

Experimental method

X-RAY DIFFRACTION (3.02 Å)