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4Y1X

Complex of human Galectin-1 and Galbeta1-4(6OSO3)GlcNAc

Summary for 4Y1X
Entry DOI10.2210/pdb4y1x/pdb
Related4Y1U 4Y1V 4Y1Y 4Y1Z 4Y20 4Y22 4Y24 4Y26
DescriptorGalectin-1, beta-D-galactopyranose-(1-4)-methyl 2-acetamido-2-deoxy-6-O-sulfo-beta-D-glucopyranoside (3 entities in total)
Functional Keywordscomplex, galectin-1, sulfated lacnac, galbeta1-4(6oso3)glcnac, sugar binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight34744.81
Authors
Lin, H.Y.,Hsieh, T.J.,Lin, C.H. (deposition date: 2015-02-09, release date: 2016-04-06, Last modification date: 2020-07-29)
Primary citationLin, H.Y.,Hsieh, T.J.,Tu, Z.,Huang, B.S.,Wu, S.C.,Chien, C.T.,Hsu, S.T.,Lin, C.H.
Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.45 Å)
Structure validation

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