4XZ2

Human platelet phosphofructokinase in an R-state in complex with ADP and F6P, crystal form I

Summary for 4XZ2

Entry DOI	10.2210/pdb4xz2/pdb
Related	3OPY 4OMT 4RH3 4U1R 4WLO
Descriptor	ATP-dependent 6-phosphofructokinase, platelet type, PHOSPHATE ION, 1,6-di-O-phosphono-beta-D-fructofuranose, ... (5 entities in total)
Functional Keywords	human platelet phosphofructokinase, fructose 6-phosphate, transferase, main regulator of glycolysis
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm : Q01813
Total number of polymer chains	4
Total formula weight	335949.06
Authors	Kloos, M.,Strater, N. (deposition date: 2015-02-03, release date: 2015-06-03, Last modification date: 2024-01-10)
Primary citation	Kloos, M.,Bruser, A.,Kirchberger, J.,Schoneberg, T.,Strater, N. Crystal structure of human platelet phosphofructokinase-1 locked in an activated conformation. Biochem.J., 469:421-432, 2015 Cited by PubMed: 26205495 DOI: 10.1042/BJ20150251 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.67 Å)

Structure validation