4XWH

Crystal structure of the human N-acetyl-alpha-glucosaminidase

Summary for 4XWH

Entry DOI	10.2210/pdb4xwh/pdb
Descriptor	Alpha-N-acetylglucosaminidase, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	glycosidase, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	83177.53
Authors	Birrane, G.,Meiyappan, M.,Dassier, A. (deposition date: 2015-01-28, release date: 2016-02-03, Last modification date: 2023-09-27)
Primary citation	Birrane, G.,Dassier, A.L.,Romashko, A.,Lundberg, D.,Holmes, K.,Cottle, T.,Norton, A.W.,Zhang, B.,Concino, M.F.,Meiyappan, M. Structural characterization of the alpha-N-acetylglucosaminidase, a key enzyme in the pathogenesis of Sanfilippo syndrome B. J.Struct.Biol., 205:65-71, 2019 Cited by PubMed: 30802506 DOI: 10.1016/j.jsb.2019.02.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.32 Å)

Structure validation