4XGQ

Crystal structure of addiction module from Mycobacterial species

Summary for 4XGQ

• Entry DOI: 10.2210/pdb4xgq/pdb
• Related: 4XGR
• Descriptor: Ribonuclease VapC30, Antitoxin VapB30, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: mycobacteria, addiction module, toxin-antitoxin complex, toxin/antitoxin
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); More
• Total number of polymer chains: 8
• Total formula weight: 94287.91

Authors

Lee, B.-J.,Lee, I.-G.,Lee, S.J. (deposition date: 2015-01-02, release date: 2015-08-12, Last modification date: 2024-03-20)

• Primary citation: Lee, I.-G.,Lee, S.J.,Chae, S.,Lee, K.Y.,Kim, J.H.,Lee, B.-J.; Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides; Nucleic Acids Res., 43:7624-7637, 2015; PubMed: 26150422; DOI: 10.1093/nar/gkv689

Experimental method

X-RAY DIFFRACTION (2.7 Å)