4XDO

Crystal structure of human KDM4C catalytic domain with OGA

Summary for 4XDO

• Entry DOI: 10.2210/pdb4xdo/pdb
• Related: 2xml 4XDP
• Descriptor: Lysine-specific demethylase 4C, ZINC ION, FE (III) ION, ... (8 entities in total)
• Functional Keywords: lysine-specific demethylase 4c, oxidoreductase
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : Q9H3R0
• Total number of polymer chains: 2
• Total formula weight: 79905.39

Authors

Swinger, K.K.,Boriack-Sjodin, P.A. (deposition date: 2014-12-19, release date: 2015-03-25, Last modification date: 2024-02-28)

• Primary citation: Wigle, T.J.,Swinger, K.K.,Campbell, J.E.,Scholle, M.D.,Sherrill, J.,Admirand, E.A.,Boriack-Sjodin, P.A.,Kuntz, K.W.,Chesworth, R.,Moyer, M.P.,Scott, M.P.,Copeland, R.A.; A High-Throughput Mass Spectrometry Assay Coupled with Redox Activity Testing Reduces Artifacts and False Positives in Lysine Demethylase Screening.; J Biomol Screen, 20:810-820, 2015; PubMed: 25755264; DOI: 10.1177/1087057115575689

Experimental method

X-RAY DIFFRACTION (1.97 Å)