4X9V

PLK-1 polo-box domain in complex with Bioactive Imidazolium-containing phosphopeptide macrocycle 3C

Summary for 4X9V

• Entry DOI: 10.2210/pdb4x9v/pdb
• Related: 4X9R 4X9W
• Descriptor: Serine/threonine-protein kinase PLK1, Phosphopeptide macrocycle 3C (3 entities in total)
• Functional Keywords: macrocycle inhibitor complex, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus: P53350
• Total number of polymer chains: 2
• Total formula weight: 28273.30

Authors

Grant, R.A.,Qian, W.-J.,Yaffe, M.B.,Burke, T.R. (deposition date: 2014-12-11, release date: 2015-07-29, Last modification date: 2023-11-15)

• Primary citation: Qian, W.J.,Park, J.E.,Grant, R.,Lai, C.C.,Kelley, J.A.,Yaffe, M.B.,Lee, K.S.,Burke, T.R.; Neighbor-directed histidine N ( tau )-alkylation: A route to imidazolium-containing phosphopeptide macrocycles.; Biopolymers, 104:663-673, 2015; PubMed: 26152807; DOI: 10.1002/bip.22698

Experimental method

X-RAY DIFFRACTION (1.429 Å)