4X97

Crystal structure of Lysosomal Phospholipase A2 in complex with methyl arachidonyl fluorophosphonate (MAFP)

Summary for 4X97

Entry DOI	10.2210/pdb4x97/pdb
Related	4X90 4X91 4X92 4X93 4X94 4X95 4X96
Descriptor	Group XV phospholipase A2, 2-acetamido-2-deoxy-beta-D-glucopyranose, METHYL ARACHIDONYL FLUOROPHOSPHONATE, ... (7 entities in total)
Functional Keywords	hydrolase, phospholipase, mafp, acyltransferase, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	178873.92
Authors	Glukhova, A.,Tesmer, J.J.G. (deposition date: 2014-12-11, release date: 2015-03-11, Last modification date: 2023-09-27)
Primary citation	Glukhova, A.,Hinkovska-Galcheva, V.,Kelly, R.,Abe, A.,Shayman, J.A.,Tesmer, J.J. Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase. Nat Commun, 6:6250-6250, 2015 Cited by PubMed: 25727495 DOI: 10.1038/ncomms7250 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.65 Å)

Structure validation