4X8Y

Crystal structure of human PGRMC1 cytochrome b5-like domain

Summary for 4X8Y

Entry DOI	10.2210/pdb4x8y/pdb
Descriptor	Membrane-associated progesterone receptor component 1, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
Functional Keywords	receptor, membrane, membrane protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	31015.64
Authors	Nakane, T.,Yamamoto, T.,Shimamura, T.,Kobayashi, T.,Kabe, Y.,Suematsu, M. (deposition date: 2014-12-11, release date: 2016-03-23, Last modification date: 2020-02-05)
Primary citation	Kabe, Y.,Nakane, T.,Koike, I.,Yamamoto, T.,Sugiura, Y.,Harada, E.,Sugase, K.,Shimamura, T.,Ohmura, M.,Muraoka, K.,Yamamoto, A.,Uchida, T.,Iwata, S.,Yamaguchi, Y.,Krayukhina, E.,Noda, M.,Handa, H.,Ishimori, K.,Uchiyama, S.,Kobayashi, T.,Suematsu, M. Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance Nat Commun, 7:11030-11030, 2016 Cited by PubMed: 26988023 DOI: 10.1038/ncomms11030 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation