4X6R

An Isoform-specific Myristylation Switch Targets RIIb PKA Holoenzymes to Membranes

Summary for 4X6R

• Entry DOI: 10.2210/pdb4x6r/pdb
• Related: 4X6Q
• Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type I-alpha regulatory subunit, SULFATE ION, ... (9 entities in total)
• Functional Keywords: pka, membrane binding, molecular switch, transferase
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 2
• Total formula weight: 75071.27

Authors

Zhang, P.,Ye, F.,Bastidas, A.C.,Kornev, A.P.,Ginsberg, M.H.,Wu, J.,Taylor, S.S. (deposition date: 2014-12-09, release date: 2015-07-22, Last modification date: 2020-06-24)

• Primary citation: Zhang, P.,Ye, F.,Bastidas, A.C.,Kornev, A.P.,Wu, J.,Ginsberg, M.H.,Taylor, S.S.; An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes.; Structure, 23:1563-1572, 2015; PubMed: 26278174; DOI: 10.1016/j.str.2015.07.007

Experimental method

X-RAY DIFFRACTION (2.4 Å)