4X6F
CD1a binary complex with sphingomyelin
Summary for 4X6F
Entry DOI | 10.2210/pdb4x6f/pdb |
Related | 4X6B 4X6C 4X6D 4X6E |
Descriptor | T-cell surface glycoprotein CD1a, Beta-2-microglobulin, (4S,7S,23Z)-4-hydroxy-7-[(1S,2Z)-1-hydroxyhexadec-2-en-1-yl]-N,N,N-trimethyl-9-oxo-3,5-dioxa-8-aza-4-phosphadotriacont- 23-en-1-aminium 4-oxide, ... (4 entities in total) |
Functional Keywords | cd1a, immune complex, lipid antigen, tcr, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane; Single-pass type I membrane protein: P06126 Secreted : P61769 |
Total number of polymer chains | 2 |
Total formula weight | 45351.29 |
Authors | Birkinshaw, R.W.,Rossjohn, J. (deposition date: 2014-12-08, release date: 2015-02-04, Last modification date: 2023-10-25) |
Primary citation | Birkinshaw, R.W.,Pellicci, D.G.,Cheng, T.Y.,Keller, A.N.,Sandoval-Romero, M.,Gras, S.,de Jong, A.,Uldrich, A.P.,Moody, D.B.,Godfrey, D.I.,Rossjohn, J. alpha beta T cell antigen receptor recognition of CD1a presenting self lipid ligands. Nat.Immunol., 16:258-266, 2015 Cited by PubMed: 25642819DOI: 10.1038/ni.3098 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.91 Å) |
Structure validation
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