4X52

Human PARP13 (ZC3HAV1), C-Terminal PARP Domain (H810N; N830Y variant)

Summary for 4X52

• Entry DOI: 10.2210/pdb4x52/pdb
• Related: 2x5y
• Descriptor: Zinc finger CCCH-type antiviral protein 1, GLYCEROL, SULFATE ION, ... (4 entities in total)
• Functional Keywords: antiviral defense, immune system, parp, zap, mutant
• Biological source: Homo sapiens (Human)
• Cellular location: Isoform 1: Cytoplasm. Isoform 2: Cytoplasm: Q7Z2W4
• Total number of polymer chains: 4
• Total formula weight: 81985.33

Authors

Karlberg, T.,Thorsell, A.G.,Klepsch, M.,Schuler, H. (deposition date: 2014-12-04, release date: 2015-02-11, Last modification date: 2024-01-10)

• Primary citation: Karlberg, T.,Klepsch, M.,Thorsell, A.G.,Andersson, C.D.,Linusson, A.,Schuler, H.; Structural Basis for Lack of ADP-ribosyltransferase Activity in Poly(ADP-ribose) Polymerase-13/Zinc Finger Antiviral Protein.; J.Biol.Chem., 290:7336-7344, 2015; PubMed: 25635049; DOI: 10.1074/jbc.M114.630160

Experimental method

X-RAY DIFFRACTION (2.08 Å)