4WYQ
Crystal structure of the Dicer-TRBP interface
Summary for 4WYQ
| Entry DOI | 10.2210/pdb4wyq/pdb |
| Descriptor | Endoribonuclease Dicer, RISC-loading complex subunit TARBP2, Poly(UNK) (3 entities in total) |
| Functional Keywords | rna interference, microrna, dsrbp, dsrbd, hydrolase-protein binding complex, hydrolase/protein binding |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 6 |
| Total formula weight | 47024.95 |
| Authors | Wilson, R.C.,Doudna, J.A. (deposition date: 2014-11-18, release date: 2014-12-17, Last modification date: 2019-12-25) |
| Primary citation | Wilson, R.C.,Tambe, A.,Kidwell, M.A.,Noland, C.L.,Schneider, C.P.,Doudna, J.A. Dicer-TRBP Complex Formation Ensures Accurate Mammalian MicroRNA Biogenesis. Mol.Cell, 57:397-407, 2015 Cited by PubMed: 25557550DOI: 10.1016/j.molcel.2014.11.030 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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