4WXX

The crystal structure of human DNMT1(351-1600)

Summary for 4WXX

• Entry DOI: 10.2210/pdb4wxx/pdb
• Descriptor: DNA (cytosine-5)-methyltransferase 1, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
• Functional Keywords: dnmt1, dna methytransferase1, dna methylation, transferase
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : P26358
• Total number of polymer chains: 2
• Total formula weight: 285626.91

Authors

Zhang, Z.M.,Song, J. (deposition date: 2014-11-14, release date: 2015-07-15, Last modification date: 2024-02-28)

• Primary citation: Zhang, Z.M.,Liu, S.,Lin, K.,Luo, Y.,Perry, J.J.,Wang, Y.,Song, J.; Crystal Structure of Human DNA Methyltransferase 1.; J.Mol.Biol., 427:2520-2531, 2015; PubMed: 26070743; DOI: 10.1016/j.jmb.2015.06.001

Experimental method

X-RAY DIFFRACTION (2.622 Å)