4WIP

DIX domain of human Dvl2

Summary for 4WIP

• Entry DOI: 10.2210/pdb4wip/pdb
• Related: 3PZ8
• Descriptor: Segment polarity protein dishevelled homolog DVL-2, PENTAETHYLENE GLYCOL (3 entities in total)
• Functional Keywords: polymer signaling ubiquitin-like, signaling protein
• Biological source: Homo sapiens (Human)
• Cellular location: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side : O14641
• Total number of polymer chains: 3
• Total formula weight: 33626.01

Authors

Fiedler, M.,Bienz, M.,Madrzak, J.,Chin, J.W. (deposition date: 2014-09-26, release date: 2015-05-13)

• Primary citation: Madrzak, J.,Fiedler, M.,Johnson, C.M.,Ewan, R.,Knebel, A.,Bienz, M.,Chin, J.W.; Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization.; Nat Commun, 6:6718-6718, 2015; PubMed: 25907794; DOI: 10.1038/ncomms7718

Experimental method

X-RAY DIFFRACTION (2.691 Å)