4WF2

Structure of E. coli BirA G142A bound to biotinol-5'-AMP

Summary for 4WF2

• Entry DOI: 10.2210/pdb4wf2/pdb
• Descriptor: Bifunctional ligase/repressor BirA, ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE (3 entities in total)
• Functional Keywords: biotin protein ligase, biotin repressor, g142a mutant, complex with biotinol-5'-amp, ligase
• Biological source: Escherichia coli
• Total number of polymer chains: 1
• Total formula weight: 36754.35

Authors

Eginton, C.,Beckett, D.,Wade, H. (deposition date: 2014-09-11, release date: 2014-10-22, Last modification date: 2023-12-27)

• Primary citation: Eginton, C.,Cressman, W.J.,Bachas, S.,Wade, H.,Beckett, D.; Allosteric Coupling via Distant Disorder-to-Order Transitions.; J.Mol.Biol., 427:1695-1704, 2015; PubMed: 25746672; DOI: 10.1016/j.jmb.2015.02.021

Experimental method

X-RAY DIFFRACTION (2.31 Å)