4UWY
FGFR1 Apo structure
Summary for 4UWY
Entry DOI | 10.2210/pdb4uwy/pdb |
Related | 4UWZ 4UX0 |
Descriptor | FIBROBLAST GROWTH FACTOR RECEPTOR 1, DI(HYDROXYETHYL)ETHER, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | transferase, inhibitor, drug, cancer, fgf, receptors, growth factors, signalling |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cell membrane; Single-pass type I membrane protein: P11362 |
Total number of polymer chains | 2 |
Total formula weight | 70829.70 |
Authors | Thiyagarajan, N.,Bunney, T.,Katan, M. (deposition date: 2014-08-15, release date: 2015-02-25, Last modification date: 2024-01-10) |
Primary citation | Bunney, T.,Wan, S.,Thiyagarajan, N.,Sutto, L.,Williams, S.V.,Ashford, P.,Koss, H.,Knowles, M.A.,Gervasio, F.L.,Coveney, P.V.,Katan, M. The Effect of Mutations on Drug Sensitivity and Kinase Activity of Fibroblast Growth Factor Receptors: A Combined Experimental and Theoretical Study Ebiomedicine, 2:194-, 2015 Cited by PubMed: 26097890DOI: 10.1016/J.EBIOM.2015.02.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.305 Å) |
Structure validation
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