4UWX

Structure of liprin-alpha3 in complex with mDia1 Diaphanous- inhibitory domain

Summary for 4UWX

Entry DOI	10.2210/pdb4uwx/pdb
Descriptor	PROTEIN DIAPHANOUS HOMOLOG 1, LIPRIN-ALPHA-3, NICKEL (II) ION, ... (5 entities in total)
Functional Keywords	peptide-binding protein, actin polymerisation, rhognbps, synape maturation, cell motility, fh1, fh2 domain, actin-nucleation factor - diaphanous-related formin, peptide binding protein
Biological source	MUS MUSCULUS (HOUSE MOUSE) More
Cellular location	Cell membrane : O08808 Cytoplasm : P60469
Total number of polymer chains	4
Total formula weight	59215.46
Authors	Brenig, J.,de Boor, S.,Knyphausen, P.,Kuhlmann, N.,Wroblowski, S.,Baldus, L.,Scislowski, L.,Artz, O.,Trauschies, P.,Baumann, U.,Neundorf, I.,Lammers, M. (deposition date: 2014-08-15, release date: 2015-05-06, Last modification date: 2024-01-10)
Primary citation	Brenig, J.,De Boor, S.,Knyphausen, P.,Kuhlmann, N.,Wroblowski, S.,Baldus, L.,Scislowski, L.,Artz, O.,Trauschies, P.,Baumann, U.,Neundorf, I.,Lammers, M. Structural and Biochemical Basis for the Inhibitory Effect of Liprin-Alpha3 on Mouse Diaphanous 1 (Mdia1) Function. J.Biol.Chem., 290:14314-, 2015 Cited by PubMed: 25911102 DOI: 10.1074/JBC.M114.621946 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation