4UUU

1.7 A resolution structure of human cystathionine beta-synthase regulatory domain (del 516-525) in complex with SAM

Summary for 4UUU

Entry DOI	10.2210/pdb4uuu/pdb
Descriptor	CYSTATHIONINE BETA-SYNTHASE, S-ADENOSYLMETHIONINE, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	lyase
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm : P35520
Total number of polymer chains	2
Total formula weight	36436.01
Authors	Kopec, J.,McCorvie, T.J.,Fitzpatrick, F.,Strain-Damerell, C.,Froese, D.S.,Tallant, C.,Burgess-Brown, N.,Arrowsmith, C.,Edwards, A.,Bountra, C.,Yue, W.W. (deposition date: 2014-07-31, release date: 2014-08-13, Last modification date: 2015-01-14)
Primary citation	Mccorvie, T.J.,Kopec, J.,Hyung, S.,Fitzpatrick, F.,Feng, X.,Termine, D.,Strain-Damerell, C.,Vollmar, M.,Fleming, J.,Janz, J.M.,Bulawa, C.,Yue, W.W. Inter-Domain Communication of Human Cystathionine Beta Synthase: Structural Basis of S-Adenosyl-L-Methionine Activation. J.Biol.Chem., 289:36018-, 2014 Cited by PubMed: 25336647 DOI: 10.1074/JBC.M114.610782 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.71 Å)

Structure validation