4UU5
CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1 IN COMPLEX WITH THE CRB PEPTIDE
Summary for 4UU5
Entry DOI | 10.2210/pdb4uu5/pdb |
Related | 4UU6 |
Descriptor | MAGUK P55 SUBFAMILY MEMBER 5, PROTEIN CRUMBS HOMOLOG 1, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | cell adhesion |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Cell membrane; Peripheral membrane protein: Q8N3R9 Isoform 1: Apical cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted: P82279 |
Total number of polymer chains | 2 |
Total formula weight | 12284.67 |
Authors | Ivanova, M.E.,Purkiss, A.G.,McDonald, N.Q. (deposition date: 2014-07-24, release date: 2015-01-14, Last modification date: 2024-01-10) |
Primary citation | Ivanova, M.E.,Fletcher, G.C.,O'Reilly, N.,Purkiss, A.G.,Thompson, B.J.,McDonald, N.Q. Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove. Acta Crystallogr. D Biol. Crystallogr., 71:555-564, 2015 Cited by PubMed: 25760605DOI: 10.1107/S139900471402776X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.23 Å) |
Structure validation
Download full validation report