4UP0

Ternary crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a H3K4me2 peptide

Summary for 4UP0

Entry DOI	10.2210/pdb4up0/pdb
Descriptor	PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, HISTONE H3.1, ZINC ION, ... (4 entities in total)
Functional Keywords	transcription, wnt signalling, phd finger, bcl9l, hd1 domain
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Nucleus : Q86UU0 P68431
Total number of polymer chains	2
Total formula weight	12302.37
Authors	Miller, T.C.R.,Fiedler, M.,Rutherford, T.J.,Birchall, K.,Chugh, J.,Bienz, M. (deposition date: 2014-06-11, release date: 2014-11-05, Last modification date: 2024-01-10)
Primary citation	Miller, T.C.R.,Rutherford, T.J.,Birchall, K.,Chugh, J.,Fiedler, M.,Bienz, M. Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger. Acs Chem.Biol., 9:2864-, 2014 Cited by PubMed: 25323450 DOI: 10.1021/CB500585S PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.28 Å)

Structure validation