Summary for 4UN0
| Entry DOI | 10.2210/pdb4un0/pdb |
| Descriptor | CYCLIN-K, CYCLIN-DEPENDENT KINASE 12 (2 entities in total) |
| Functional Keywords | transferase |
| Biological source | HOMO SAPIENS (HUMAN) More |
| Cellular location | Nucleus : O75909 Q9NYV4 |
| Total number of polymer chains | 4 |
| Total formula weight | 136525.64 |
| Authors | Dixon Clarke, S.E.,Elkins, J.M.,Pike, A.C.W.,Chaikuad, A.,Goubin, S.,Krojer, T.,Sorrell, F.J.,Nowak, R.,Williams, E.,Kopec, J.,Mahajan, R.P.,Burgess-Brown, N.,Carpenter, E.P.,Knapp, S.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A. (deposition date: 2014-05-22, release date: 2014-06-04, Last modification date: 2024-01-10) |
| Primary citation | Dixon-Clarke, S.E.,Elkins, J.M.,Cheng, S.G.,Morin, G.B.,Bullock, A.N. Structures of the Cdk12/Cyck Complex with AMP-Pnp Reveal a Flexible C-Terminal Kinase Extension Important for ATP Binding. Sci.Rep., 5:17122-, 2015 Cited by PubMed: 26597175DOI: 10.1038/SREP17122 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.15 Å) |
Structure validation
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