4UJA

Protein Kinase A in complex with an Inhibitor

Summary for 4UJA

• Entry DOI: 10.2210/pdb4uja/pdb
• Related: 4UJ1 4UJ2 4UJ9 4UJB
• Descriptor: CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA, PEPTIDE, 7-{(3S,4R)-4-[(5-bromothiophen-2-yl)carbonyl]pyrrolidin-3-yl}quinazolin-4(3H)-one, ... (6 entities in total)
• Functional Keywords: transferase
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 2
• Total formula weight: 43637.34

Authors

Alam, K.A.,Engh, R.A. (deposition date: 2015-04-09, release date: 2016-04-13, Last modification date: 2024-01-10)

• Primary citation: Lauber, B.S.,Hardegger, L.A.,Asraful, A.K.,Lund, B.A.,Dumele, O.,Harder, M.,Kuhn, B.,Engh, R.A.,Diederich, F.; Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of Pka and a Pkb Mimic.; Chemistry, 22:211-, 2016; PubMed: 26578105; DOI: 10.1002/CHEM.201503552

Experimental method

X-RAY DIFFRACTION (1.93 Å)