4UIP

The complex structure of extracellular domain of EGFR with Repebody (rAC1).

Summary for 4UIP

Entry DOI	10.2210/pdb4uip/pdb
Descriptor	EPIDERMAL GROWTH FACTOR RECEPTOR, REPEBODY (RAC1), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	transferase
Biological source	HOMO SAPIENS (HUMAN) More
Total number of polymer chains	2
Total formula weight	97757.03
Authors	Kang, Y.J.,Cha, Y.J.,Cho, H.S.,Lee, J.J.,Kim, H.S. (deposition date: 2015-03-31, release date: 2015-11-25, Last modification date: 2024-01-10)
Primary citation	Lee, J.,Choi, H.,Yun, M.,Kang, Y.,Jung, J.,Ryu, Y.,Kim, T.Y.,Cha, Y.,Cho, H.,Min, J.,Chung, C.,Kim, H. Enzymatic Prenylation and Oxime Ligation for the Synthesis of Stable and Homogeneous Protein-Drug Conjugates for Targeted Therapy. Angew.Chem.Int.Ed.Engl., 54:12020-, 2015 Cited by PubMed: 26315561 DOI: 10.1002/ANIE.201505964 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.95 Å)

Structure validation