4U1A

Crystal structure of human peroxisomal delta3,delta2, enoyl-CoA isomerase helix-10 deletion mutant (ISOB-ECI2)

Summary for 4U1A

• Entry DOI: 10.2210/pdb4u1a/pdb
• Descriptor: Enoyl-CoA delta isomerase 2, CHLORIDE ION (3 entities in total)
• Functional Keywords: peci, crotonase, beta-oxidation, isomerase
• Biological source: Homo sapiens (Human)
• Cellular location: Isoform 1: Mitochondrion . Isoform 2: Peroxisome matrix: O75521
• Total number of polymer chains: 3
• Total formula weight: 89647.54

Authors

Onwukwe, G.U.,Koski, M.K.,Wierenga, R.K. (deposition date: 2014-07-15, release date: 2014-12-24, Last modification date: 2015-02-25)

• Primary citation: Onwukwe, G.U.,Kursula, P.,Koski, M.K.,Schmitz, W.,Wierenga, R.K.; Human Delta (3) , Delta (2) -enoyl-CoA isomerase, type 2: a structural enzymology study on the catalytic role of its ACBP domain and helix-10.; Febs J., 282:746-768, 2015; PubMed: 25515061; DOI: 10.1111/febs.13179

Experimental method

X-RAY DIFFRACTION (2.85 Å)