4TZI

Structure of unliganded Lyn SH2 domain

Summary for 4TZI

Entry DOI	10.2210/pdb4tzi/pdb
Descriptor	Tyrosine-protein kinase Lyn (2 entities in total)
Functional Keywords	sh2 domain, transferase
Biological source	Mus musculus (Mouse)
Cellular location	Cell membrane : P25911
Total number of polymer chains	2
Total formula weight	26398.00
Authors	Wybenga-Groot, L.E. (deposition date: 2014-07-10, release date: 2015-01-21, Last modification date: 2023-09-27)
Primary citation	Jin, L.L.,Wybenga-Groot, L.E.,Tong, J.,Taylor, P.,Minden, M.D.,Trudel, S.,McGlade, C.J.,Moran, M.F. Tyrosine Phosphorylation of the Lyn Src Homology 2 (SH2) Domain Modulates Its Binding Affinity and Specificity. Mol.Cell Proteomics, 14:695-706, 2015 Cited by PubMed: 25587033 DOI: 10.1074/mcp.M114.044404 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation