4TVQ

CCM3 in complex with CCM2 LD-like motif

Summary for 4TVQ

• Entry DOI: 10.2210/pdb4tvq/pdb
• Related: 3L8I 3L8J 3RQE 3RQF 3RQG
• Descriptor: Cerebral cavernous malformations 3 protein, Cerebral cavernous malformations 2 protein (2 entities in total)
• Functional Keywords: fat-homology domain, protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 101452.98

Authors

Li, X.,Zhang, R.,Fisher, O.S.,Boggon, T.J. (deposition date: 2014-06-27, release date: 2015-03-25, Last modification date: 2023-09-27)

• Primary citation: Draheim, K.M.,Li, X.,Zhang, R.,Fisher, O.S.,Villari, G.,Boggon, T.J.,Calderwood, D.A.; CCM2-CCM3 interaction stabilizes their protein expression and permits endothelial network formation.; J.Cell Biol., 208:987-1001, 2015; PubMed: 25825518; DOI: 10.1083/jcb.201407129

Experimental method

X-RAY DIFFRACTION (2.8 Å)