4TRQ

Crystal structure of Sac3/Thp1/Sem1

Summary for 4TRQ

Entry DOI	10.2210/pdb4trq/pdb
Descriptor	Nuclear mRNA export protein SAC3, Nuclear mRNA export protein THP1, 26S proteasome complex subunit SEM1, ... (4 entities in total)
Functional Keywords	pci domain, trex-2, gene expression, gene regulation
Biological source	Saccharomyces cerevisiae (Baker's yeast) More
Cellular location	Nucleus envelope : P46674 Q08231
Total number of polymer chains	6
Total formula weight	151771.85
Authors	Hellerschmied, D.,Schneider, S.,Kohler, A.,Clausen, T. (deposition date: 2014-06-17, release date: 2015-08-26, Last modification date: 2023-12-20)
Primary citation	Schneider, M.,Hellerschmied, D.,Schubert, T.,Amlacher, S.,Vinayachandran, V.,Reja, R.,Pugh, B.F.,Clausen, T.,Kohler, A. The Nuclear Pore-Associated TREX-2 Complex Employs Mediator to Regulate Gene Expression. Cell, 162:1016-1028, 2015 Cited by PubMed: 26317468 DOI: 10.1016/j.cell.2015.07.059 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation