4TRF
Crystal structure of Macrophage Migration Inhibitory Factor in complex with N-(pyridin-3-ylmethyl)thioformamide
Summary for 4TRF
| Entry DOI | 10.2210/pdb4trf/pdb |
| Related | 4TRS 4TRU |
| Descriptor | Macrophage migration inhibitory factor, N-(pyridin-3-ylmethyl)thioformamide, SULFATE ION, ... (6 entities in total) |
| Functional Keywords | inhibitor isomerase, complex, active site, isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor |
| Biological source | Homo sapiens (Human) |
| Cellular location | Secreted : P14174 |
| Total number of polymer chains | 3 |
| Total formula weight | 38114.39 |
| Authors | Pantouris, G.,Lolis, E. (deposition date: 2014-06-16, release date: 2015-09-30, Last modification date: 2023-12-27) |
| Primary citation | Pantouris, G.,Syed, M.A.,Fan, C.,Rajasekaran, D.,Cho, T.Y.,Rosenberg, E.M.,Bucala, R.,Bhandari, V.,Lolis, E.J. An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22:1197-1205, 2015 Cited by PubMed: 26364929DOI: 10.1016/j.chembiol.2015.08.006 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.63 Å) |
Structure validation
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