4TQS

Ternary complex of Y-family DNA polymerase Dpo4 with (5'S)-8,5'-Cyclo-2'-deoxyguanosine and dCTP

Summary for 4TQS

• Entry DOI: 10.2210/pdb4tqs/pdb
• Descriptor: DNA polymerase IV, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*T)-3'), DNA (5'-D(P*TP*CP*AP*CP*(2LF)P*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ... (7 entities in total)
• Functional Keywords: y-family dna polymerase, dna damage, cyclopurine, translesion dna synthesis, transferase, transferase-dna complex, transferase/dna
• Biological source: Sulfolobus solfataricus; More
• Total number of polymer chains: 6
• Total formula weight: 102143.35

Authors

Zhao, L. (deposition date: 2014-06-11, release date: 2015-01-14, Last modification date: 2023-12-27)

• Primary citation: Xu, W.,Ouellette, A.M.,Wawrzak, Z.,Shriver, S.J.,Anderson, S.M.,Zhao, L.; Kinetic and Structural Mechanisms of (5'S)-8,5'-Cyclo-2'-deoxyguanosine-Induced DNA Replication Stalling.; Biochemistry, 54:639-651, 2015; PubMed: 25569151; DOI: 10.1021/bi5014936

Experimental method

X-RAY DIFFRACTION (2.06 Å)