4TNE
Crystal Structure of Human Transthyretin Thr119Tyr Mutant
Summary for 4TNE
| Entry DOI | 10.2210/pdb4tne/pdb |
| Related | 4TKW 4TL4 4TL5 4TLK 4TLS 4TLT 4TLU 4TM9 4TNF 4TNG |
| Descriptor | Transthyretin, GLYCEROL (3 entities in total) |
| Functional Keywords | human transthyretin, amyloid, transthyretin, mutant, transport protein |
| Biological source | Homo sapiens (Human) |
| Cellular location | Secreted: P02766 |
| Total number of polymer chains | 2 |
| Total formula weight | 28055.38 |
| Authors | Saelices, L.,Cascio, D.,Sawaya, M.,Eisenberg, D.S. (deposition date: 2014-06-03, release date: 2015-10-21, Last modification date: 2023-12-27) |
| Primary citation | Saelices, L.,Johnson, L.M.,Liang, W.Y.,Sawaya, M.R.,Cascio, D.,Ruchala, P.,Whitelegge, J.,Jiang, L.,Riek, R.,Eisenberg, D.S. Uncovering the Mechanism of Aggregation of Human Transthyretin. J.Biol.Chem., 290:28932-28943, 2015 Cited by PubMed: 26459562DOI: 10.1074/jbc.M115.659912 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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