4ROA

1.90A resolution structure of SRPN2 (S358W) from Anopheles gambiae

Summary for 4ROA

Entry DOI	10.2210/pdb4roa/pdb
Related	4RO9 4ROB
Descriptor	Serpin 2 (2 entities in total)
Functional Keywords	serpin, serine protease inhibitor, insect immunity, hydrolase inhibitor
Biological source	Anopheles gambiae (African malaria mosquito)
Total number of polymer chains	1
Total formula weight	45462.73
Authors	Lovell, S.,Battaile, K.P.,Zhang, X.,Meekins, D.A.,An, C.,Michel, K. (deposition date: 2014-10-28, release date: 2014-12-24, Last modification date: 2023-09-20)
Primary citation	Zhang, X.,Meekins, D.A.,An, C.,Zolkiewski, M.,Battaile, K.P.,Kanost, M.R.,Lovell, S.,Michel, K. Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae. J.Biol.Chem., 290:2946-2956, 2015 Cited by PubMed: 25525260 DOI: 10.1074/jbc.M114.625665 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation