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4RNN

Crystal structure of human polymerase eta inserting dGMPnPP opposite DNA template containing an abasic site

Summary for 4RNN
Entry DOI10.2210/pdb4rnn/pdb
Related4RNM 4RNO
DescriptorDNA polymerase eta, Nucleic acids Template: CAT(3DR)ATGACGCT, Nucleic acids Primar: AGCGTCAT, ... (7 entities in total)
Functional Keywordsprotein, dna, dna damage dna-directed dna polymerase, adenosine triphosphate, y-family polymerase, trans-lesion synthesis (tls), dna binding, abasic site lesion bypass, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus : Q9Y253
Total number of polymer chains3
Total formula weight55388.71
Authors
Patra, A.,Egli, M. (deposition date: 2014-10-24, release date: 2015-02-18, Last modification date: 2023-09-20)
Primary citationPatra, A.,Zhang, Q.,Lei, L.,Su, Y.,Egli, M.,Guengerich, F.P.
Structural and Kinetic Analysis of Nucleoside Triphosphate Incorporation Opposite an Abasic Site by Human Translesion DNA Polymerase eta.
J.Biol.Chem., 290:8028-8038, 2015
Cited by
PubMed: 25666608
DOI: 10.1074/jbc.M115.637561
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.808 Å)
Structure validation

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