Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4RMS

Crystal structure of the D53N Beta-2 Microglobulin mutant

Summary for 4RMS
Entry DOI10.2210/pdb4rms/pdb
Related2YXF 4FXL 4RMQ 4RMR 4RMT 4RMU 4RMV 4RMW
DescriptorBeta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ACETATE ION, ... (4 entities in total)
Functional Keywordsimmunoglobin, beta-sandwitch, amyloidosis, pathologic mutation, genetic disease, mhc class i, immune system
Biological sourceHomo sapiens (human)
Cellular locationSecreted : P61769
Total number of polymer chains1
Total formula weight12043.54
Authors
de Rosa, M.,Bolognesi, M.,Ricagno, S. (deposition date: 2014-10-22, release date: 2015-11-18, Last modification date: 2023-09-20)
Primary citationde Rosa, M.,Barbiroli, A.,Giorgetti, S.,Mangione, P.P.,Bolognesi, M.,Ricagno, S.
Decoding the Structural Bases of D76N 2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis.
Plos One, 10:e0144061-e0144061, 2015
Cited by
PubMed: 26625273
DOI: 10.1371/journal.pone.0144061
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon