4RKK

Structure of a product bound phosphatase

Summary for 4RKK

• Entry DOI: 10.2210/pdb4rkk/pdb
• Related PRD ID: PRD_900009 PRD_900010 PRD_900035
• Descriptor: Laforin, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: dual specificity phosphatase, carbohydrate binding module, phosphatase, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 79733.25

Authors

Vander Kooi, C.W. (deposition date: 2014-10-13, release date: 2015-01-07, Last modification date: 2024-02-28)

• Primary citation: Raththagala, M.,Brewer, M.K.,Parker, M.W.,Sherwood, A.R.,Wong, B.K.,Hsu, S.,Bridges, T.M.,Paasch, B.C.,Hellman, L.M.,Husodo, S.,Meekins, D.A.,Taylor, A.O.,Turner, B.D.,Auger, K.D.,Dukhande, V.V.,Chakravarthy, S.,Sanz, P.,Woods, V.L.,Li, S.,Vander Kooi, C.W.,Gentry, M.S.; Structural mechanism of laforin function in glycogen dephosphorylation and lafora disease.; Mol.Cell, 57:261-272, 2015; PubMed: 25544560; DOI: 10.1016/j.molcel.2014.11.020

Experimental method

X-RAY DIFFRACTION (2.4 Å)