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4RK8

Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A356

Summary for 4RK8
Entry DOI10.2210/pdb4rk8/pdb
DescriptorDihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, OROTIC ACID, ... (6 entities in total)
Functional Keywordsoxidoreductase, fmn binding, mitochondria inner membrane, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationMitochondrion inner membrane ; Single-pass membrane protein : Q02127
Total number of polymer chains1
Total formula weight44697.95
Authors
Zhu, L.,Ren, X.,Zhu, J.,Li, H. (deposition date: 2014-10-12, release date: 2015-11-11, Last modification date: 2023-09-20)
Primary citationZhu, L.,Ren, X.,Zhu, J.,Li, H.
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A356
TO BE PUBLISHED,
Experimental method
X-RAY DIFFRACTION (2.22 Å)
Structure validation

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