4R1F
Re-refined Human DNA topoisomerase IIa (ATPase and transducer domains) in complex with ADP and SO4
Summary for 4R1F
| Entry DOI | 10.2210/pdb4r1f/pdb |
| Related | 1EI1 1ZXM 4PRX 4prv 4pu9 |
| Descriptor | DNA topoisomerase 2-alpha, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (6 entities in total) |
| Functional Keywords | human topoisomerase iia, isomerase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm : P11388 |
| Total number of polymer chains | 4 |
| Total formula weight | 184828.45 |
| Authors | Stanger, F.V.,Schirmer, T. (deposition date: 2014-08-05, release date: 2014-09-24, Last modification date: 2023-11-08) |
| Primary citation | Stanger, F.V.,Dehio, C.,Schirmer, T. Structure of the N-Terminal Gyrase B Fragment in Complex with ADPPi Reveals Rigid-Body Motion Induced by ATP Hydrolysis Plos One, 9:e107289-e107289, 2014 Cited by PubMed: 25202966DOI: 10.1371/journal.pone.0107289 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.51 Å) |
Structure validation
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