4R0X

Allosteric coupling of conformational transitions in the FK1 domain of FKBP51 near the site of steroid receptor interaction

Summary for 4R0X

Entry DOI	10.2210/pdb4r0x/pdb
Descriptor	Peptidyl-prolyl cis-trans isomerase FKBP5 (2 entities in total)
Functional Keywords	fk-506 binding domain, hsp90 cochaperone, immunophiline, peptidyl-prolyl isomerase, isomerase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q13451
Total number of polymer chains	1
Total formula weight	13487.48
Authors	LeMaster, D.M.,Mustafi, S.M.,Brecher, M.,Zhang, J.,Heroux, A.,Li, H.M.,Hernandez, G. (deposition date: 2014-08-02, release date: 2015-05-13, Last modification date: 2023-09-20)
Primary citation	LeMaster, D.M.,Mustafi, S.M.,Brecher, M.,Zhang, J.,Heroux, A.,Li, H.,Hernandez, G. Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins. J.Biol.Chem., 290:15746-15757, 2015 Cited by PubMed: 25953903 DOI: 10.1074/jbc.M115.650655 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation