4QVE

Crystal structure of Bcl-xL in complex with BID BH3 domain

Summary for 4QVE

• Entry DOI: 10.2210/pdb4qve/pdb
• Related: 1MAZ 4QVF
• Descriptor: Bcl-2-like protein 1, Peptide from BH3-interacting domain death agonist, IMIDAZOLE, ... (4 entities in total)
• Functional Keywords: protein-peptide complex, bcl-2 like, heterodimer, apoptosis, anti-apoptotic, bh3 binding, bid bh3
• Biological source: Homo sapiens (human); More
• Cellular location: Isoform Bcl-X(L): Mitochondrion inner membrane : Q07817; Cytoplasm . BH3-interacting domain death agonist p15: Mitochondrion membrane . BH3-interacting domain death agonist p13: Mitochondrion membrane . Isoform 1: Cytoplasm. Isoform 3: Cytoplasm. Isoform 2: Mitochondrion membrane: P55957
• Total number of polymer chains: 2
• Total formula weight: 23075.41

Authors

Sreekanth, R.,Yoon, H.S. (deposition date: 2014-07-14, release date: 2015-06-10, Last modification date: 2023-11-08)

• Primary citation: Rajan, S.,Choi, M.,Baek, K.,Yoon, H.S.; Bh3 induced conformational changes in Bcl-Xl revealed by crystal structure and comparative analysis.; Proteins, 83:1262-1272, 2015; PubMed: 25907960; DOI: 10.1002/prot.24816

Experimental method

X-RAY DIFFRACTION (2.05 Å)