4QPM

Structure of Bub1 kinase domain

Summary for 4QPM

Entry DOI	10.2210/pdb4qpm/pdb
Descriptor	Mitotic checkpoint serine/threonine-protein kinase BUB1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	transferase
Biological source	Homo sapiens (human)
Cellular location	Nucleus: O43683
Total number of polymer chains	2
Total formula weight	83313.32
Authors	Lin, Z.H.,Jia, L.Y.,Tomchick, D.R.,Luo, X.L.,Yu, H.T. (deposition date: 2014-06-24, release date: 2014-10-22, Last modification date: 2014-12-24)
Primary citation	Lin, Z.,Jia, L.,Tomchick, D.R.,Luo, X.,Yu, H. Substrate-Specific Activation of the Mitotic Kinase Bub1 through Intramolecular Autophosphorylation and Kinetochore Targeting. Structure, 22:1616-1627, 2014 Cited by PubMed: 25308863 DOI: 10.1016/j.str.2014.08.020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.202 Å)

Structure validation