4Q7H

Crystal structure of SAMHD1 catalytic core with GTP

Summary for 4Q7H

• Entry DOI: 10.2210/pdb4q7h/pdb
• Related: 3U1N 4BZB 4BZC 4MZ7
• Descriptor: Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ZINC ION, GUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: protein-gtp complex, hydrolase, hd-domain, dntp binding, phosphorylation, gtp
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : Q9Y3Z3
• Total number of polymer chains: 4
• Total formula weight: 246222.04

Authors

Xiaohong, Q.,Yanhong, L.,Jia, K.,Xiaofang, Y. (deposition date: 2014-04-25, release date: 2015-05-27, Last modification date: 2017-10-04)

• Primary citation: Xiaohong, Q.,Yanhong, L.,Jia, K.,Xiaofang, Y.; Structural insight into activation mechanism of SAMHD1; To be Published,

Experimental method

X-RAY DIFFRACTION (2.587 Å)