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4PRY

Caspase-8 specific unnatural amino acid peptides

Summary for 4PRY
Entry DOI10.2210/pdb4pry/pdb
Related4JJ7 4JJ8 4JJE 4PRZ 4PS0 4PS1
DescriptorCaspase-3, Ac-LETD-CHO (3 entities in total)
Functional Keywordsprotease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P42574
Total number of polymer chains2
Total formula weight33208.61
Authors
Wolan, D.W.,Gonzalez-Paez, G.E.,Vickers, C.J. (deposition date: 2014-03-06, release date: 2015-01-21, Last modification date: 2023-12-06)
Primary citationVickers, C.J.,Gonzalez-Paez, G.E.,Litwin, K.M.,Umotoy, J.C.,Coutsias, E.A.,Wolan, D.W.
Selective inhibition of initiator versus executioner caspases using small peptides containing unnatural amino acids.
Acs Chem.Biol., 9:2194-2198, 2014
Cited by
PubMed: 25079698
DOI: 10.1021/cb5004256
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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