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4POM

Crystal structures of thioredoxin with mesna at 1.85A resolution

Summary for 4POM
Entry DOI10.2210/pdb4pom/pdb
Related4POK 4POL
DescriptorThioredoxin, 1-THIOETHANESULFONIC ACID (3 entities in total)
Functional Keywordsoxidoreductase
Biological sourceHomo sapiens (human)
Cellular locationNucleus: P10599
Total number of polymer chains4
Total formula weight48488.61
Authors
Sridhar, V.,Chie-Leon, B.,Badger, J.,Nienaber, V.L.,Hausheer, F.H. (deposition date: 2014-02-26, release date: 2014-10-29, Last modification date: 2023-09-20)
Primary citationParker, A.R.,Nienaber, V.L.,Petluru, P.N.,Sridhar, V.,Leverett, B.D.,Ayala, P.Y.,Zhao, M.,Chie-Leon, B.,Jair, K.,Kochat, H.,Badger, J.,Hausheer, F.H.
BNP7787 Forms Novel Covalent Adducts on Human Thioredoxin and Modulates Thioredoxin Activity
J Pharmacol Clin Toxicol, 2:1026-, 2014
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

218500

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