4PM1

Human transthyretin (TTR) complexed with 16-alpha-bromo-estradiol

Summary for 4PM1

Entry DOI	10.2210/pdb4pm1/pdb
Related	3GS0 3GS4 4PME 4PMF
Descriptor	Transthyretin, (14beta,16alpha,17alpha)-16-bromoestra-1,3,5(10)-triene-3,17-diol, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	human transthyretin hydrophobic ligand solubilization, thyroid hormone-binding protein
Biological source	Homo sapiens (Human)
Cellular location	Secreted: P02766
Total number of polymer chains	2
Total formula weight	28381.41
Authors	Stura, E.A.,Ciccone, L. (deposition date: 2014-05-20, release date: 2014-10-08, Last modification date: 2023-09-27)
Primary citation	Ciccone, L.,Tepshi, L.,Nencetti, S.,Stura, E.A. Transthyretin complexes with curcumin and bromo-estradiol: evaluation of solubilizing multicomponent mixtures. N Biotechnol, 32:54-64, 2014 Cited by PubMed: 25224922 DOI: 10.1016/j.nbt.2014.09.002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.23 Å)

Structure validation