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4P7A

Crystal Structure of human MLH1

Replaces:  3NA3
Summary for 4P7A
Entry DOI10.2210/pdb4p7a/pdb
DescriptorDNA mismatch repair protein Mlh1, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
Functional Keywordsstructural genomics consortium, dna mismatch repair, dna damage, sgc, dna binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight39106.51
Authors
Tempel, W.,Lam, R.,Zeng, H.,Walker, J.R.,Loppnau, P.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Wu, H.,Structural Genomics Consortium (SGC) (deposition date: 2014-03-26, release date: 2014-04-09, Last modification date: 2023-12-27)
Primary citationWu, H.,Zeng, H.,Lam, R.,Tempel, W.,Kerr, I.D.,Min, J.
Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome.
Acta Crystallogr.,Sect.F, 71:981-985, 2015
Cited by
PubMed: 26249686
DOI: 10.1107/S2053230X15010183
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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