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4P6W

Crystal Structure of mometasone furoate-bound glucocorticoid receptor ligand binding domain

Summary for 4P6W
Entry DOI10.2210/pdb4p6w/pdb
Related4P6X
DescriptorGlucocorticoid receptor, Nuclear receptor coactivator 2, MOMETASONE FUROATE, ... (4 entities in total)
Functional Keywordsmometasone furoate, glucocorticoid receptor, potency, hormone-hormone receptor complex, hormone receptor-hormone activator complex, hormone receptor/hormone activator
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight31212.09
Authors
He, Y.,Zhou, X.E.,Tolbert, W.D.,Powell, K.,Melcher, K.,Xu, H.E. (deposition date: 2014-03-25, release date: 2014-04-16, Last modification date: 2023-12-27)
Primary citationHe, Y.,Yi, W.,Suino-Powell, K.,Zhou, X.E.,Tolbert, W.D.,Tang, X.,Yang, J.,Yang, H.,Shi, J.,Hou, L.,Jiang, H.,Melcher, K.,Xu, H.E.
Structures and mechanism for the design of highly potent glucocorticoids.
Cell Res., 24:713-726, 2014
Cited by
PubMed: 24763108
DOI: 10.1038/cr.2014.52
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.951 Å)
Structure validation

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