4P4H

Caught-in-action signaling complex of RIG-I 2CARD domain and MAVS CARD domain

Summary for 4P4H

• Entry DOI: 10.2210/pdb4p4h/pdb
• Descriptor: Probable ATP-dependent RNA helicase DDX58, Mitochondrial antiviral-signaling protein, Ubiquitin-60S ribosomal protein L40 (3 entities in total)
• Functional Keywords: signaling protein, signaling complex
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm: O95786; Mitochondrion outer membrane: Q7Z434; Ubiquitin: Cytoplasm . 60S ribosomal protein L40: Cytoplasm : P62987
• Total number of polymer chains: 21
• Total formula weight: 334392.81

Authors

Wu, B.,Hur, S. (deposition date: 2014-03-12, release date: 2014-07-30, Last modification date: 2023-12-27)

• Primary citation: Wu, B.,Peisley, A.,Tetrault, D.,Li, Z.,Egelman, E.H.,Magor, K.E.,Walz, T.,Penczek, P.A.,Hur, S.; Molecular Imprinting as a Signal-Activation Mechanism of the Viral RNA Sensor RIG-I.; Mol.Cell, 55:511-523, 2014; PubMed: 25018021; DOI: 10.1016/j.molcel.2014.06.010

Experimental method

X-RAY DIFFRACTION (3.4 Å)